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Feasibility and safety of weaning premature infants from nasal continuous positiv airway pressure to high-flow nasal cannula: a prospective observational case study
- Research
- Open access
- Published:
BMC Pediatricsvolume 24, Article number: 741 (2024) Cite this article
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Abstract
Background
Nasal continuous positive airway pressure (NCPAP) is widely used for premature infants with respiratory distress syndrome (RDS). A high-flow nasal cannula (HFNC) provides positiv end-expiratory pressure using high-flow oxygen; however, the variability in distending pressure is a primary concern. This study evaluated the feasibility and safety of a newly designed protocol for NCPAP weaning with cyclic HFNC use for premature infants.
Methods
Premature infants with RDS using NCPAP support who were ready for weaning were enrolled. The weaning protocol used cyclic NCPAP with HFNC every 3 h for 3 days in the neonatal intensive care
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Abstract
Background
The aim is to establish and verify reference intervals (RIs) for serum tumor markers for an apparently healthy elderly population in Southwestern China using an indirect method.
Methods
Data from 35,635 apparently healthy elderly individuals aged 60 years and above were obtained in West China Hospital from April 2020 to December 2021. We utilized the Box-Cox conversion combined with the Tukey method to normalize the data and eliminate outliers. Subgroups are divided according to gender and age to examine the division of RIs. The Z-test was used to compare differences between groups, and 95% distribution RIs were calculated using a nonparametric method.
Results
In the study, we observed that the RIs for serum ferritin and Des-γ-carboxy prothrombin (DCP) were wider for men, ranging from 64.18 to 865.80 ng/ml and 14.00 to 33.00 mAU/ml, respectively, compared to women, whose ranges were 52.58 to 585.88 ng/ml and 13.00 to 29.00 mAU/ml. For other biomarkers, the
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Pre-cluster symptoms in a Taiwanese cohort of cluster headache: symptom profiles and clinical predictions
- Research
- Open access
- Published:
- Jr-Wei Wu1,2na1,
- Shu-Ting Chen2,3na1,
- Yen-Feng Wang1,2,
- Shih-Pin Chen1,4,5,
- Shin-Yi Tseng1,
- Yih-Shiuan Kuo2,6,
- Wei-Ta Chen1,2,7,8,
- Chia-Chun Chiang9 &
- …
- Shuu-Jiun Wang1,2,7
The Journal of Headache and Painvolume 25, Article number: 174 (2024) Cite this article
Abstract
Background
Pre-cluster symptoms (PCSs) are symptoms preceding cluster bouts and might have implications for the treatment of cluster headache (CH). This study investigated the prevalence of PCSs, and their utility in predicting upcoming bouts as well as the associations with therapeutic efficacy.
Methods
We prospectively collected data from patients with CH. Each patient received a structured interview and completed questionnaire surveys during CH bouts. In sub-study 1, we cross-sectionally analyzed the prevalence, s